Does the emptiness ever go away?

First of all, I am very sorry that you are suffering from depression to such an extent that you cannot enjoy anything in life. Is there anything in your past that could be contributing to your depression? Such as abuse, etc.? I suggest you see a good professional, GOOD being the operative word, not all psychologists are created equal. If you can get a reference from someone you know, or someone online in your area, that would be much better than picking someone out of the yellow pages! If this has been going on for a long time, it isn't likely to go away on it's own. It's caused by one of two things 1) something from your past that hasn't been dealt with or 2) a chemical imbalance in the brain that is causing depression. A qualified therapist can identify the issue and resolve it. Best of luck, and let me know if you need a way to find a therapist in your area by getting in touch with someone online who sees a qualified therapist with empathy, the empathy is key! You mention you have seen a therapist, but you don't mention for how long you saw one, or why it didn't work. It's important to find one who has empathy, and who when and if they do prescribe medication, that it's the right medication. Sometimes it takes a few tries to find the correct medication. You may not need medication at all, there is cognitive therapy, and sometimes a mix of the two.